Tohoku University
3 papers in the library · 81 citations · publishing 1981-1986
Journal of Natural Products May 1, 1981 Yutaka Koike, Kohko Wada, Genjiro Kusano et al. 45 citations
Psilocybin was isolated from the mushroom Psilocybe argentipes and its presence was determined in specimens of several mushroom species. The work details the chemical isolation and analytical methods used to identify and quantify the alkaloid in these fungi.
Chemical and Pharmaceutical Bulletin January 1, 1986 Genjiro Kusano, Yutaka Koike, Hideo Inoue et al. 21 citations
From a hallucinogenic mushroom, Gymnopilus spectabilis, two compounds were isolated and characterized: cerevisterol and a new acetylenic compound, 4,6-decadiyne-1,3,8-triol. Also found were ergosterol, ergosteryl peroxide, and choline. Psilocybin and related psychoactive compounds were not detected in these collections, although psilocybin has been found in other Japanese mushrooms.
The Tohoku Journal of Experimental Medicine January 1, 1986 Morihiro Musha, Atsushi Ishii, Fumio Tanaka et al. 15 citations
Five cases of poisoning by the indigenous mushroom Hikageshibiretake (Psilocybe argentipes) are described. Since this mushroom contains psilocybin, clinical features generally resembled those of pure psilocybin. One case involved an acute toxic stuporous state with complete amnesia during the culminating period, one case involved a psychedelic state with dreamy consciousness, and three cases involved psychotic adverse reactions with vivid visual hallucinations while conscious. These experiences were accompanied by anxiety and panic reactions. Although the toxic effects were usually short-lived, the report emphasizes that horrible emotional reactions and harmful behavioral problems can occur, which is important for patient management.